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C14308 Vadimezan(DMXAA) (117570-53-3)

Catalog No.:	C14308
CAS No.:	117570-53-3
Synonym:	NSC-640488,ASA404,DMXAA
Chemical Name:	5,6-Dimethylxantheonone-4-acetic acid; 2-(5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid
Molecular Formula:	C₁₇H₁₄O₄
Molecular Weight:	282.29

Technical Data:

Appearance:	White powder
Solubility:	Soluble in DMSO
Purity:	>98%
Storage:	at +4°C
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Vadimezan(DMXAA):

Size	Price	Stock
10mg	USD	In stock
50mg	USD	In stock
100mg	USD	In stock

Biological Activity:

Vadimezan or ASA404 (originally DMXAA)is a tumor-vascular disrupting agent(tumor-VDA) that attacks the blood supply of a cancerous tumor to cause tumor regression.It is being studied for the treatment of prostate cancer and HER2 -negative metastatic breast cancer.

References:

Tang CK et al. The chemotherapeutic agent DMXAA as a unique IRF3-dependent type-2 vaccine adjuvant.PLoS One 8:e60038 (2013).

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