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ICONC13690 FTY720(Fingolimod HCl) (162359-56-0)
 
 
Catalog No.: C13690
CAS No.: 162359-56-0
Synonym: Fingolimod HCl
Chemical Name:

2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol HCl
Molecular Formula:

C19H33NO2.HCl
Molecular Weight: 343.93
 
Technical Data:
Appearance: White to off-white crystalline powder
Solubility: Soluble in DMSO
Purity: >99%
Storage: at -20℃
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of FTY720(Fingolimod HCl):

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10mg 

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50mg 

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100mg 

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Contact us for competitive discounts on bulk quantities
 
Biological Activity:

Novel immune modulator that alters migration and homing of lymphocytes. Acts as a potent agonist of sphingosine 1-phosphate receptors (S1P) after phosphorylation by sphingosine kinase. Also inhibits cytosolic phospholipase A2 independently of sphingosine 1-phosphate receptors.
 
References:
Wallington-Beddoe CT, et al. Disparate in vivo efficacy of FTY720 in xenograft models of Philadelphia positive and negative B-lineage acute lymphoblastic leukemia. PLoS One. 2012, 7(5), e36429.
 
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