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ICONC14320 Varenicline tartrate (375815-87-5)
 
 
Catalog No.: C14320
CAS No.: 375815-87-5
Synonym: CP 526555-18; Champix tartrate; Chantix tartrate
Chemical Name:

7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]b enzazepine tartrate

Molecular Formula: C17H19N3O6
Molecular Weight: 361.37
 
Technical Data:
Appearance: White powder
Solubility: Soluble in water
Purity: >99%
Storage: Store at room temperature
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Varenicline tartrate:

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10mg 

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50mg 

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100mg 

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Biological Activity:

Orally active, subtype-selective partial agonist at α4β2 nicotinic receptors (Ki values are 0.06, 240, 322 and 3540 nM for α4β2, α3β4, α7, α1βγδ receptors respectively). Reduces nicotine-evoked dopamine release in vitro and decreases nicotine self-administration in vivo.

 
References:
Coe JW  et al. Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation. J Med Chem 48:3474-7 (2005).
 
View Related Products by Target:
Cyclopamine(11-Deoxyjervine)
(+)-Egenine
 
 

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