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ICONC14030 Pirfenidone (53179-13-8)
 
 
Catalog No.: C14030
CAS No.: 53179-13-8
Synonym: Esbriet; AMR69; Deskar; Pirespa
Chemical Name:

5-Methyl-1-phenyl-2-(1H)-pyridone

Molecular Formula:

C12H11NO

Molecular Weight: 185.22
 
Technical Data:
Appearance: White crystal powder
Solubility: Soluble in DMSO
Purity: >99%
Storage: Store at room temperature
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Pirfenidone:

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Biological Activity:

Antifibrotic agent, effective in models of pulmonary and lung fibrosis. Inhibits collagen production and fibroblast proliferation. Regulates cytokine levels following oral administration in vivo. Potent scavenger of free radicals and inhibitor of lipid peroxidation.

 
References:

1.Nakazato H, et al. Eur J Pharmacol, 2002, 446(1-3), 177-185.

2. Burghardt I, et al. Biochem Biophys Res Commun, 2007, 354(2), 542-547.

 
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