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ICONC14066 Prucalopride(R-93877) (179474-81-8)
 
 
Catalog No.: C14066
CAS No.: 179474-81-8
Synonym: R-93877
Chemical Name:

4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide.
Molecular Formula:

C18H26Cl N3O3
Molecular Weight: 367.87
 
Technical Data:
Appearance: White to off-white powder
Solubility: Soluble in DMSO and Methanol
Purity: >99%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Prucalopride(R-93877):

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10mg 

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50mg 

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100mg 

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Contact us for competitive discounts on bulk quantities
 
Biological Activity:

Selective 5-HT4 receptor agonist; a gastroprokinetic agent for the treatment of constipation and irritable bowel syndrome; showed memory-enhancing effects in mice through modulation of cholinergic pathways; hence an indication of potential as Alzheimer's disease therapy.
 
References:
Bouras EP, et al. Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans. Gut. 1999 May;44(5):682-6.
 
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