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ICONC14332 Vincristine sulfate(Leurocristine sulfate salt) (2068-78-2)
 
 
Catalog No.: C14332
CAS No.: 2068-78-2
Synonym: Leurocristine sulfate salt
Chemical Name:
22-Oxovincaleukoblastine sulfate salt
Molecular Formula:

C46H58N4O14S
Molecular Weight: 923.04
 
Technical Data:
Appearance:
Solubility: Soluble in water
Purity: >98%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Vincristine sulfate(Leurocristine sulfate salt):

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Biological Activity:
Anticancer agent; microtubule disrupter. Induces apoptosis in human lymphoma cells.
 
References:

1. Varma H  et al. Mutant huntingtin alters cell fate in response to microtubule depolymerization via the GEF-H1-RhoA-ERK pathway. J Biol Chem 285:37445-57 (2010).

2. Jordan MA  et al. Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro. Cancer Res 45:2741-7 (1985).
 
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