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C14175 Sitagliptin phosphate monohydrate (654671-77-9)

Catalog No.:	C14175
CAS No.:	654671-77-9
Synonym:	MK-0431 phosphate monohydrate; Januvia phosphate monohydrate
Chemical Name:	7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate monohydrate
Molecular Formula:	C₁₆H₁₅F₆N₅O^.H₃PO₄^.H₂O
Molecular Weight:	523.33

Technical Data:

Appearance:
Solubility:	Soluble in Water
Purity:	>99%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Sitagliptin phosphate monohydrate:

Size	Price	Stock
10mg	USD	In stock
50mg	USD	In stock
100mg	USD	In stock

Biological Activity:

Sitagliptin(MK 0431) phosphate monohydrate is a potent inhibitor of DPP4 with IC50 of 19 nM in Caco-2 cell extracts.

References:

1. Thomas L et al. J Pharmacol Exp Ther. 2008; 325(1): 175-182.

2. Kim SJ et al. Diabetes. 2009; 58(3): 641-651.

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