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ICONC13430 CaCCinh-A01 (407587-33-1)
 
 
Catalog No.: C13430
CAS No.: 407587-33-1
Synonym: CaCCinh-A01;CaCC(inh)-A01
Chemical Name:
6-(1,1-Dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid
Molecular Formula: C18H21NO4S
Molecular Weight: 347.43
 
Technical Data:
Appearance:
Solubility: Soluble in DMSO and ethanol
Purity: >98%
Storage: Store at -20°C
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of CaCCinh-A01:

Size

Price

Stock

50mg 

USD360

In Stock 

100mg 

USD650

In Stock 

500mg 

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Biological Activity:
Calcium-activated chloride channel (CaCC) inhibitor (IC50 ~ 10 μM). Inhibits CaCC currents in human bronchial and intestinal cells. Also inhibits TMEM16A channels (IC50 = 2.1 μM, in TMEM16A-expressing FRT cells).
 
References:
De La Fuente et al (2008) Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloride channel. Mol.Pharmacol. 73 758.
 
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