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ICONC16234 Go 6983 (Goe 6983) (133053-19-7)
 
 
Catalog No.: C16234
CAS No.: 133053-19-7
Synonym: Goe 6983;Go6983
Chemical Name:
3-[1-[3-(Dimethylamino)propyl]-5-me​thoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-​2,5-dione;2-[1-(3-Dimethylaminopropyl)-5-methoxyindol-3-yl]-3-(1H-indol-3-yl) maleimide
Molecular Formula:

C26H26N4O3
C26H26N4O3
C26H26N4O3

Molecular Weight: 442.51
 
Technical Data:
Appearance:
Solubility: Soluble in DMSO
Purity: >98%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Go 6983 (Goe 6983):

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10mg 

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25mg 

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50mg 

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Contact us for competitive discounts on bulk quantities

 
Biological Activity:
Broad spectrum protein kinase C (PKC) inhibitor (IC50 values are 7, 7, 6, 10, 60 and 20000 nM for PKCα, PKCβ, PKCγ, PKCδ, PKCζ and PKCμ respectively). Displays cardioprotective properties; reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury.
 
References:
1. Gschwendt M, et al. FEBS Lett, 1996, 392(2), 77-80. 

2. Peterman EE, et al. J Cardiovasc Pharmacol, 2004, 43(5), 645-656.
 
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