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ICONC13804 LDN-193189 (1062368-24-4)
 
 
Catalog No.: C13804
CAS No.: 1062368-24-4
Synonym: DM3189; LDN 193189
Chemical Name:
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
Molecular Formula: C25H22N6
Molecular Weight: 406.48
 
Technical Data:
Appearance:
Solubility:
Purity: 98%+Min.
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Biological Activity:
LDN-193189 is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β.
 
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