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ICONC13380 Bicalutamide (90357-06-5)
 
 
Catalog No.: C13380
CAS No.: 90357-06-5
Synonym: Cosudex; Casodex
Chemical Name:

N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methyl-propanamide
Molecular Formula:

C18H14F4N2O4S
Molecular Weight: 430.37
 
Technical Data:
Appearance: White crystal powder
Solubility: Soluble in DMSO
Purity: >99%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Bicalutamide:

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10mg 

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50mg 

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100mg 

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Biological Activity:

A nonsteroidal antiandrogen, which has been shown effective in the treatment of prostate cancer. It has also been shown to induce cell death by a pathway that is independent of changes in mitochondrial membrane potential and Bcl-2 actions.
 
References:

Maucher A, von Angerer E. J Canc Res Clin Oncol. 119:669-74 (1993).
Lee EC, Zhan P, Schallhom R et al. Cell Death &Differentiation. 10:761-71 (2003).
 
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