Soluble in chloroform, ethyl acetate, ethanol and methanol, Insoluble in water
Purity:
>98%
Storage:
at +4℃
Original QC Data:
Shipping Conditions:
Ambient Temp.
Price and Availability of Pristimerin:
Size
Price
Stock
10mg
USD
In stock
50mg
USD
In stock
100mg
USD
In stock
Contact us for competitive discounts on bulk quantities
Biological Activity:
Triterpenoid. Antitumor agent. Induces caspase-dependent apoptosis by inhibiting the chymotrypsin-like activity of the proteasome. Inhibits NF-κB activation via inhibition of IKKα or IKKβ. Inhibits induction of inducible nitric oxide synthase (iNOS; NOS II). Shows in vitro antimalarial and insecticidal activity. Induces mitochondrial cell death. Has antiproliferative, antifungal and antiviral properties. Potent and reversible monoacylglycerol lipase (MGL) inhibitor.
References:
Kinget al(2009) Discovery of potent and reversible monoacylglycerol lipase inhibitors. Chem.Biol.161045.