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Vitamin D series compounds

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C13240 A 769662 (844499-71-4)

Catalog No.:	C13240
CAS No.:	844499-71-4
Synonym:	Thieno[2,3-b]pyridine-5-carbonitrile, 6,7-dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo
Chemical Name:	6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl )-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile
Molecular Formula:	C20H12N2O3S
Molecular Weight:	360.39

Technical Data:

Appearance:	Off-white powder
Solubility:	Soluble in DMSO, slightly Soluble in ethanol
Purity:	>99%
Storage:	Store at or below -20 ºC
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of A 769662:

Size	Price	Stock
50mg	USD260	In stock
100mg	USD500	In stock
300mg	USD950	In stock
500mg	USD1500	In stock

Biological Activity:

Specific activator of AMP dependent protein kinase (AMPK);A-769662 also delays the onset of tumours in mice lacking the tumour suppressor PTEN [6], suggesting a potential anti-cancer role.

References:

Benziane B et al. AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase.Am J Physiol Cell Physiol 297:C1554-66 (2009).

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