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ICONC13246 Abiraterone(CB-7598) (154229-19-3)
 
 
Catalog No.: C13246
CAS No.: 154229-19-3
Synonym: CB-7598; CB7598; CB 7598
Chemical Name:

17-(3-Pyridyl)androsta-5,16-dien-3beta-ol

Molecular Formula:

C24H31NO

Molecular Weight: 349.51
 
Technical Data:
Appearance: White or off-white powder
Solubility: Soluble in DMSO
Purity: >99%
Storage: at -20℃
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Abiraterone(CB-7598):

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10mg 

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50mg 

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100mg 

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Contact us for competitive discounts on bulk quantities

 
Biological Activity:
A potential agent for the treatment of prostatic cancer; P450 17(17 alpha-hydroxylase /C17-20-lyase) inhibitor
 
References:

1.Pinto-Bazurco Mendieta, Mariano A. E.; Synthesis, Biological Evaluation, and Molecular Modeling of Abiraterone Analogues: Novel CYP17 Inhibitors for the Treatment of Prostate Cancer. Journal of Medicinal Chemistry (2008), 51(16), 5009-5018.
2. Attard G et al. Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer. J Clin Oncol. 2009 Aug 10;27(23):3742-8.

 
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