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C13895 Mitomycin C(Ametycine) (50-07-7)

Catalog No.:	C13895
CAS No.:	50-07-7
Synonym:	Ametycine;mutamycin
Chemical Name:	[1aS-(1aa,8b,8aa,8ba)]-6-Amino-8-[[(aminocarbonyl)oxy]m ethyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazir ino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione
Molecular Formula:	C₁₅H₁₈N₄O₅
Molecular Weight:	334.33

Technical Data:

Appearance:	Violet-Blue Crystal
Solubility:	Soluble in DMSO and Methanol
Purity:	>97%
Storage:	at +4°C
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Mitomycin C(Ametycine):

Size	Price	Stock
10mg	USD	In stock
50mg	USD	In stock
100mg	USD	In stock

Biological Activity:

Antibiotic and antitumor agent. Covalently binds DNA forming intra- and interstrand crosslinks. Inhibits DNA synthesis.

References:

1.Tomasz M, Lipman R, Chowdary D, Pawlak J, Verdine GL, Nakanishi K. Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA. Science. 1987 Mar 6;235(4793):1204-8.
2. Bizanek R, McGuinness BF, Nakanishi K, Tomasz M. Isolation and structure of an intrastrand cross-link adduct of mitomycin C and DNA. Biochemistry. 1992 Mar 31;31(12):3084-91.

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