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ICONC13967 Oxaliplatin(Eloxatin) (61825-94-3)
 
 
Catalog No.: C13967
CAS No.: 61825-94-3
Synonym: Foloxatine;Transplatin;Eloxatin;Eloxatine
Chemical Name:

trans-L-Diaminocyclohexane oxalatoplatinum

Molecular Formula:

C8H12N2O4Pt

Molecular Weight: 395.27
 
Technical Data:
Appearance: White or almost white crystalline powder
Solubility: Slightly soluble in water ,very slightly solublein methanol, practically insoluble in ethanol
Purity: >99%
Storage: at +4℃
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Oxaliplatin(Eloxatin):

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10mg 

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50mg 

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100mg 

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Contact us for competitive discounts on bulk quantities

 
Biological Activity:

Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Displays higher cytotoxicity and lower nephrotoxicity than analog cisplatin and shows antitumor activity in cell lines with acquired cisplatin resistance.

 
References:
Faivre S  et al. DNA strand breaks and apoptosis induced by oxaliplatin in cancer cells. Biochem Pharmacol66:225-37 (2003).
 
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