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ICONC14036 Plerixafor (110078-46-1)
 
 
Catalog No.: C14036
CAS No.: 110078-46-1
Synonym: JM 3100,AMD3100
Chemical Name:

1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane
Molecular Formula:

C28H54N8
Molecular Weight: 502.78
 
Technical Data:
Appearance: White powder
Solubility: Freely Soluble in water ,in ethanol and in etherl
Purity: >99%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Plerixafor:

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50mg 

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Biological Activity:

A macrocyclic compound and potential fusion inhibitor. It is an antagonist (or perhaps more accurately a partial agonist) of the alpha-chemokine receptor CXCR4 & an allosteric agonist of CXCR7.

 
 
References:

1. Zabel BA, et al. J Immunol. 2009, 183(5), 3204-3211.

2. Fricker SP, et al. Biochem Pharmacol. 2006, 72(5), 588-596.
 
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