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C14143 Saquinavir mesylate (149845-06-7)

Catalog No.:	C14143
CAS No.:	149845-06-7
Synonym:	RO 31-8959
Chemical Name:	(2S)-N1[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2-(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide Mesylate; Butanediamide, N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)-, monomethanesulfonate (salt) (9CI); Butanediamide, N1-[3-[3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, [3S-[2[1R(R),2S*],3a,4ab,8ab]]-, monomethanesulfonate (salt)
Molecular Formula:	C₃₈H₅₀N₆O₅^.CH₄O₃S
Molecular Weight:	766.95

Technical Data:

Appearance:	White or almost white powder
Solubility:	Soluble in Methanol and Water
Purity:	>99%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Saquinavir mesylate :

Size	Price	Stock
50mg	USD200	In stock
100mg	USD360	In stock
1g	Get quote

Biological Activity:

A selective HIV protease inhibitor

References:

1.Brouwers J, Vermeire K, Grammen C, Schols D, Augustijns P. Early identification of availability issues for poorly water-soluble microbicide candidates in biorelevant media: a case study with saquinavir. Antiviral Res. 2011 Aug;91(2):217-23.
2. Knechten H, Lutz T, Pulik P, Martin T, Tappe A, Jaeger H. Safety and Efficacy in HIV-1-Infected Patients Treated with Ritonavir-Boosted Saquinavir Mesylate.

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