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ICONC13998 Peramivir(BCX-1812) (330600-85-6)
 
 
Catalog No.: C13998
CAS No.: 330600-85-6
Synonym: RWJ-270201, BCX-1812
Chemical Name:
(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic acid
Molecular Formula:
C15H28N4O4
Molecular Weight: 328.4102
 
Technical Data:
Appearance:
Solubility: Freely soluble in water
Purity: >99%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Peramivir(BCX-1812):

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Biological Activity:

Peramivir is an experimental antiviral drug for the treatment of influenza. It has been authorized for the emergency use of treatment of certain hospitalized patients with known or suspected 2009 H1N1 influenza. Peramivir is a neuraminidase inhibitor, acting as a transition-state analogue inhibitor of influenza neuraminidase and thereby preventing new viruses from emerging from infected cells.

 
References:
1.Abed Y, Pizzorno A, Boivin G. Therapeutic Activity of Intramuscular Peramivir in Mice Infected with a Recombinant Influenza A/WSN/33 (H1N1) Virus Containing the H275Y Neuraminidase Mutation. Antimicrob Agents Chemother. 2012 Aug;56(8):4375-80.
2. Hikita T, Hikita H, Hikita F, Hikita N, Hikita S. Clinical effectiveness of peramivir in comparison with other neuraminidase inhibitors in pediatric influenza patients.Int J Pediatr. 2012;2012:834181. 
 
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