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ICONC14328 Vicriviroc Maleate (599179-03-0)
 
 
Catalog No.: C14328
CAS No.: 599179-03-0
Synonym: SCH 417690
Chemical Name:

1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate

Molecular Formula:

C28H38F3N5O2.C4H4O4

Molecular Weight: 649.71
 
Technical Data:
Appearance:
Solubility: Soluble in DMSO
Purity: >99%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Vicriviroc Maleate:

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10mg 

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50mg 

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100mg 

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Contact us for competitive discounts on bulk quantities

 
Biological Activity:

Second generation orally active CCR5 antagonist, which is also a potent inhibitor of HIV-1 entry into target cells, with a mean IC₅₀ =0.46 nM and IC₉₀ =1~10 nM to HIV isolates (n=52)

 
References:

Maltêz, Fernandoa; Doroana, Manuelab; Branco, Teresac et al. Recent advances in antiretroviral treatment and prevention in HIV-infected patients. Current Opinion in HIV & AIDS. 2011 ,6:S21-S30.

 
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