Buy L-Biopterin(NSC 339699)|22150-76-1|Inhibitors|from supplier chembestbuy.com|Research only

Home

Add Favorites

Search Product

Live Chat

E-mail

Pharmacology

Inhibitors

Receptors

Hedgehog Signaling Pathway

Research Area

Cardiovascular System

Product Type

Vitamin D series compounds

Toxins

　 More +

Browse Alphabetically by Name

ALL	A	B	C	D	E	F
G	H	I	J	K	L	M
N	O	P	Q	R	S	T
U	V	W	X	Y	Z	Others

C13803 L-Biopterin(NSC 339699) (22150-76-1)

Catalog No.:	C13803
CAS No.:	22150-76-1
Synonym:	6-Biopterin;NSC 339699; L-erythro-Biopterin
Chemical Name:	(1'R,2'S)-Biopterin; 2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine
Molecular Formula:	C₉H₁₁N₅O₃
Molecular Weight:	237.09

Technical Data:

Appearance:	pale yellow powder
Solubility:	Soluble in ethanol
Purity:	>98%
Storage:	Store at room temperature
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of L-Biopterin(NSC 339699):

Size	Price	Stock
10mg	USD	In stock
50mg	USD	In stock
100mg	USD	In stock

Biological Activity:

L-Biopterin is the oxidized form of tetrahydro-L-biopterin (BH₄), a nitric oxide synthase (NOS) cofactor. L-Biopterin can be reduced to BH₄ via thioredoxin reductase followed by dihydropteridine reductase or reduced glutathione. It is extremely toxic to human melanocytes in culture (IC₅₀ = 0.2 µM after 48 hrs). L-Biopterin is rarely found under physiological conditions except in the epidermis of patients with the depigmentation disorder Vitiligo.

References:

Weinberg JB et al. Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages.Blood 86:1184-95 (1995).

View Related Products by Target:

Vandetanib(AZD6474)

Vorinostat(SAHA)

Tozasertib(VX-680)

Lenalidomide(CC-5013)

Sunitinib Malate(Sutent)