Buy NS-398|123653-11-2|Inhibitors|from supplier chembestbuy.com|Research only

Home

Add Favorites

Search Product

Live Chat

E-mail

Pharmacology

Inhibitors

Receptors

Hedgehog Signaling Pathway

Research Area

Cardiovascular System

Product Type

Vitamin D series compounds

Toxins

　 More +

Browse Alphabetically by Name

ALL	A	B	C	D	E	F
G	H	I	J	K	L	M
N	O	P	Q	R	S	T
U	V	W	X	Y	Z	Others

C13941 NS-398 (123653-11-2)

Catalog No.:	C13941
CAS No.:	123653-11-2
Synonym:	N-[2-(Cyclohexoxy)-4-Nitro-Phenyl]Methanesulfonamide; N-[2-(Cyclohexoxy)-4-Nitrophenyl]Methanesulfonamide; N-(2-Cyclohexyloxy-4-Nitro-Phenyl)Methanesulfonamide
Chemical Name:	N-[2-(cyclohexyloxy)-4-nitrophenyl]-methanesulfonamide
Molecular Formula:	C₁₃H₁₈N₂O₅S
Molecular Weight:	314.4

Technical Data:

Appearance:
Solubility:	Soluble in DMSO
Purity:	>99%
Storage:	Store at room temperature
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of NS-398:

Size	Price	Stock
10mg	USD	In stock
50mg	USD	In stock
100mg	USD	In stock

Biological Activity:

Selective cyclooxygenase-2 inhibitor (IC₅₀ values are 3.8 and > 100 μM for COX-2 and COX-1 respectively). Induces apoptosis in colorectal tumor cells and elevates COX-2 protein expression in vitro. Orally active and non-ulcerogenic analgesic and anti-inflammatory in vivo.

References:

Du Y et al. Induction of apoptosis and cell cycle arrest by NS398 in oral squamous cell carcinoma cells via downregulation of E2 promoter-binding factor-1. Oncol Rep 20:605-11 (2008).

View Related Products by Target:

Vandetanib(AZD6474)

Vorinostat(SAHA)

Tozasertib(VX-680)

Lenalidomide(CC-5013)

Sunitinib Malate(Sutent)