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ICONC13618 Entecavir monohydrate (209216-23-9)
 
 
Catalog No.: C13618
CAS No.: 209216-23-9
Synonym: Baraclude
Chemical Name:

2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate

Molecular Formula:

C12H17N5O4

Molecular Weight: 295.29448
 
Technical Data:
Appearance: white or off-white powder
Solubility: Soluble in DMSO
Purity: >99%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Entecavir monohydrate:

Size

Price

Stock

10mg 

USD

In Stock 

50mg 

USD

In Stock 

100mg 

USD

In Stock 

Contact us for competitive discounts on bulk quantities

 
Biological Activity:

Entecaviris an oral antiviral drug used in the treatment of hepatitis B infection. Entecavir is a nucleoside analog (more specifically, a guanine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process. Entecavir is more efficacious than previous agents used to treat hepatitis B (lamivudine and adefovir). Entecavir is also indicated for the treatment of chronic hepatitis B in adults with HIV/AIDS infection. However, entecavir is not active against HIV.

 
References:
Hagiwara S, et al. Impact of peginterferon alpha-2b and entecavir hydrate combination therapy on persistent viral suppression in patients with chronic hepatitis B. J Med Virol. 2013 Jun;85(6):987-95.
 
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