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ICONC13293 Anacetrapib(MK0859) (875446-37-0)
 
 
Catalog No.: C13293
CAS No.: 875446-37-0
Synonym: MK0859
Chemical Name:
(4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-3-[[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl]-4-methyl-1,3-oxazolidin-2-one;(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-[[4'-fluoro-2'-methoxy-5'-(1-methylethyl)-4-(trifluoromethyl)[1,1'-biphenyl]-2-yl]methyl]-4-methyl-2-Oxazolidinone
Molecular Formula:

C30H25F10NO3

Molecular Weight: 637.51
 
Technical Data:
Appearance:
Solubility: Soluble in DMSO
Purity: >97.5%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Anacetrapib(MK0859):

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10mg 

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50mg 

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100mg 

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Contact us for competitive discounts on bulk quantities

 
Biological Activity:
Anacetrapib (MK-0859) is a CETP inhibitor being developed to treat hypercholesterolemia(elevated cholesterol levels) and prevent cardiovascular disease.
 
References:
1. Ranalletta M, et al. Biochemical characterization of cholesteryl ester transfer protein inhibitors. J Lipid Res. 2010, 51(9), 2739-2752.
2. Tan EY, et al. Pharmacokinetics, metabolism, and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in rats and rhesus monkeys. Drug Metab Dispos. 2010, 38(3), 459-473.
 
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