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Vitamin D series compounds

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C13537 Darunavir (206361-99-1)

Catalog No.:	C13537
CAS No.:	206361-99-1
Synonym:	TMC114; TMC-114; TMC 114
Chemical Name:	[(3R,3aS,6aR)-2,3,3a,4,5,6a-Hexahydrofuro[5,4-b]furan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate
Molecular Formula:	C₂₇H₃₇N₃O₇S
Molecular Weight:	547.66

Technical Data:

Appearance:	White to off-white crystal powder
Solubility:	Soluble in DMSO and Ethanol
Purity:	>99%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Darunavir:

Size	Price	Stock
10mg	USD	In stock
50mg	USD	In stock
100mg	USD	In stock

Biological Activity:

HIV-1 antiviral structurally similar to amprenavir. Second generation HIV-1-protease inhibitor.

References:

Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003) Arasteh, K., et al.: AIDS, 19, 943 (2005) Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005)

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