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ICONC13537 Darunavir (206361-99-1)
 
 
Catalog No.: C13537
CAS No.: 206361-99-1
Synonym: TMC114; TMC-114; TMC 114
Chemical Name:
[(3R,3aS,6aR)-2,3,3a,4,5,6a-Hexahydrofuro[5,4-b]furan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate
Molecular Formula: C27H37N3O7S
Molecular Weight: 547.66
 
Technical Data:
Appearance: White to off-white crystal powder
Solubility: Soluble in DMSO and Ethanol
Purity: >99%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Darunavir:

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10mg 

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50mg 

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100mg 

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Contact us for competitive discounts on bulk quantities

 
Biological Activity:

HIV-1 antiviral structurally similar to amprenavir. Second generation HIV-1-protease inhibitor.

 
References:

Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003) Arasteh, K., et al.: AIDS, 19, 943 (2005) Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005)

 
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