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ICONC14091 Rebamipide (111911-87-6(139344-42-6,90098-04-7) )
 
 
Catalog No.: C14091
CAS No.: 111911-87-6(139344-42-6,90098-04-7)
Synonym:
Chemical Name:
2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-quinolyl)propionic acid
Molecular Formula: C19H15ClN2O4
Molecular Weight: 370.07
 
Technical Data:
Appearance:
Solubility: Soluble in DMSO and Ethanol
Purity: >98%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Rebamipide:

Size

Price

Stock

10mg 

USD

In Stock 

25mg 

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In Stock 

50mg 

USD

In Stock 

Contact us for competitive discounts on bulk quantities

 
Biological Activity:

Rebamipide, an amino acid derivative of 2-(1H)-quinolinone, is used for mucosal protection, healing of gastroduodenal ulcers, and treatment of gastritis. It works by 

enhancing mucosal defense, scavenging free radicals, and temporarily activating genes encoding cyclooxygenase-2.Studies have shown that Rebamipide can fight the 

damaging effects of NSAIDs on the GIT mucosa, and more recently, the small intestine.It has also been used for the treatment of Behçet's disease.

 
References:
  1. Arakawa T  et al. 15th anniversary of rebamipide: looking ahead to the new mechanisms and new applications.Dig Dis Sci 50 Suppl 1:S3-S11 (2005).
  2. Kohashi M  et al. Effective treatment with oral administration of rebamipide in a mouse model of Sjögren's syndrome. Arthritis Rheum 58:389-400 (2008).
 
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