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ICONC14067 Prulifloxacin (123447-62-1)
 
 
Catalog No.: C14067
CAS No.: 123447-62-1
Synonym: NM441; NM 441; NM-441
Chemical Name:
(+/-)-7-{4-[(Z)-2,3-Dihydroxy-2-butenyl]-1-piperazinyl}-6-fluoro-1-methyl-4-oxo-1H,4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid cyclic carbonate; 6-Fluoro-1-methyl-7-(4-(5-methyl-2-oxo-1,3-dioxelen-4-yl)methyl-1-piperazinyl)-4-oxo-4H-(1,3)thiazeto(3,2-a)quinoline-3-carboxylic acid
Molecular Formula: C21H20FN3O6S
Molecular Weight: 461.46
 
Technical Data:
Appearance:
Solubility: Soluble in DMSO and Ethanol
Purity: >99%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Prulifloxacin:

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10mg 

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Biological Activity:
Broad spectrum quinoline antibiotic agent. Prodrug of ulifloxacin. Shows activity against a variety of Gram-positive and -negative bacteria. Orally active
 
References:

1. Nandi U  et al. Correlation among the toxicity profiling (28-days repeated oral dose toxicity), toxicokinetics and tissue distribution data of ulifloxacin, the active metabolite of prulifloxacin in Wistar albino rats. Environ Toxicol Pharmacol 34:588-607 (2012)

2. Huang Y  et al. Investigation on interaction of prulifloxacin with pepsin: a spectroscopic analysis. Spectrochim Acta A Mol Biomol Spectrosc 75:1024-9 (2010).

 
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