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C14359 Zalcitabine(Dideoxycytidine,2'-3'-dideoxycytidine, ddC) (7481-89-2)

Catalog No.:	C14359
CAS No.:	7481-89-2
Synonym:	2'-3'-dideoxycytidine, ddC
Chemical Name:	2',3'-Dideoxycytidine
Molecular Formula:	C₉H₁₃N₃O₃
Molecular Weight:	211.22

Technical Data:

Appearance:
Solubility:	Soluble in DMSO
Purity:	>98%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Zalcitabine(Dideoxycytidine,2'-3'-dideoxycytidine, ddC):

Size	Price	Stock
10mg	USD	In Stock
25mg	USD	In Stock
50mg	USD	In Stock

Biological Activity:

Nucleoside reverse transcriptase inhibitor (NRTI). Pyrimidine nucleoside analog, substrate for reverse transcriptase. Able to induce oxidative stress. Effective against HIV replication in vivo.

References:

1. Opii WO et al. Oxidative stress and toxicity induced by the nucleoside reverse transcriptase inhibitor (NRTI)--2',3'-dideoxycytidine (ddC): relevance to HIV-dementia. Exp Neurol 204:29-38 (2007).

2. Brown TA & Clayton DA Release of replication termination controls mitochondrial DNA copy number after depletion with 2',3'-dideoxycytidine. Nucleic Acids Res 30:2004-10 (2002).

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