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ICONCL1079 Abiraterone(CB-7598) (154229-19-3)
 
 
Catalog No.: CL1079
CAS No.: 154229-19-3
Synonym: CB-7598; CB7598; CB 7598
Chemical Name:

17-(3-Pyridyl)androsta-5,16-dien-3beta-ol

Molecular Formula:

C24H31NO

Molecular Weight: 349.51
 
Technical Data:
Appearance: White or off-white powder
Solubility: Soluble in DMSO
Purity: >99%
Storage: at -20℃
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Abiraterone(CB-7598):

Size

Price

Stock

25 mg

USD 40

 In stock 

50 mg

USD 50

 In stock 

100 mg

USD 60

 In stock 

250 mg

USD 70

 In stock 

500 mg

USD 100

 In stock 

1 g

USD 136

 In stock 

Contact us for competitive discounts on bulk quantities

 
Biological Activity:
A potential agent for the treatment of prostatic cancer; P450 17(17 alpha-hydroxylase /C17-20-lyase) inhibitor
 
References:

1.Pinto-Bazurco Mendieta, Mariano A. E.; Synthesis, Biological Evaluation, and Molecular Modeling of Abiraterone Analogues: Novel CYP17 Inhibitors for the Treatment of Prostate Cancer. Journal of Medicinal Chemistry (2008), 51(16), 5009-5018.
2. Attard G et al. Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer. J Clin Oncol. 2009 Aug 10;27(23):3742-8.

 
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