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CL2273 Tandutinib(CT 53518) (387867-13-2)

Catalog No.:	CL2273
CAS No.:	387867-13-2
Synonym:	MLN518,CT53518
Chemical Name:	4-[6-Methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide; (4-(6-Methoxy-7-(3-piperidylpropoxy)quinazolin-4-yl)piperazinyl)-N-(4-(methylethoxy)phenyl)carboxamide
Molecular Formula:	C₃₁H₄₂N₆O₄
Molecular Weight:	562.70

Technical Data:

Appearance:	Yellowish powder
Solubility:	Soluble in DMSO and chloroform
Purity:	>99%
Storage:	at -20° C
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Tandutinib(CT 53518):

Size	Price	Stock
200 mg	USD 188	In stock
500 mg	USD 288	In stock
1 g	USD 528	In stock

Biological Activity:

An oral tyrosine kinase inhibitor (TKI), targeting FLT3 (FMS-Like Tyrosine kinase-3), c-KIT and PDGFR, thereby inhibiting cellular proliferation and inducing apoptosis.

References:

1. Brownlow, N., et al. 2008. Leukemia. 22: 1452-1453. PMID: 18185521
2. DeAngelo, D.J., et al. 2006. Blood. 108: 3674-3681. PMID: 16902153

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