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Vitamin D series compounds

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C13718 Glimepiride(Amaryl) (93479-97-1)

Catalog No.:	C13718
CAS No.:	93479-97-1
Synonym:	Amaryl
Chemical Name:	1-[[p-[2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea
Molecular Formula:	C₂₄H₃₄N₄O₅S
Molecular Weight:	490.62

Technical Data:

Appearance:
Solubility:	Soluble in DMSO and Ethanol
Purity:	>98%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Glimepiride(Amaryl):

Size	Price	Stock
10mg	USD	In stock
50mg	USD	In stock
100mg	USD	In stock

Biological Activity:

Potent K_ir6 (K_ATP) channel blocker and anti-diabetic agent. Inhibits pinacidil-activated cardiac K_ir6 channels with an IC₅₀ of 6.8 nM.

References:

Effect of metabolic inhibition on glimepiride block of native and cloned cardiac sacrolemmal KATP channels. Lawrence, C.L., et al. Br. J. Pharmacol. 136, 746-752, (2002)

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