Buy Sunitinib Malate(Sutent)|341031-54-7|Inhibitors|from supplier chembestbuy.com|Research only

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C14200 Sunitinib Malate(Sutent) (341031-54-7)

Catalog No.:	C14200
CAS No.:	341031-54-7
Synonym:	SU-11248;PHA-290940AD;PNU-290940AD
Chemical Name:	N-(2-(Diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-hydroxybutanedioate
Molecular Formula:	C₂₂H₂₇FN₄O₂^.C₄H₆O₅
Molecular Weight:	532.56

Technical Data:

Appearance:	Pale brown to brown powder
Solubility:	Soluble in DMSO
Purity:	>99%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Sunitinib Malate(Sutent):

Size	Price	Stock
10mg	USD	In stock
50mg	USD	In stock
100mg	USD	In stock

Biological Activity:

Small molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. Sunitinib inhibits cellular signaling by targeting multiple RTKs, including PDGF-R/VEGF-R

References:

RJ Motzer et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007, 356(2), 115–124. doi:10.1056/NEJMoa065044. PMID 17215529

ED Deeks and GM Keating. Sunitinib. Drugs 2006, 66, 2255-2266.

TJ Abrams, et al. SU11248 Inhibits KIT and Platelet-derived Growth Factor Receptor β in Preclinical Models of Human Small Cell Lung Cancer. Mol. Cancer Ther. 2003, 2, 471-478.

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