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ICONC16403 Darbufelone (139226-28-1)
 
 
Catalog No.: C16403
CAS No.: 139226-28-1
Synonym: Darbufelone;5-((Z)-3,5-Di-tert-butyl-4-hydroxybenzylidene)-2-imino-4-thiazolidinone; (5Z)-2-Amino-5-[(4-hydroxy-3,5-ditert-butyl-phenyl)methylidene]-1,3-thiazol-4-one
Chemical Name:
(5Z)-2-Amino-5-[(4-hydroxy-3,5-ditert-butyl-phenyl)methylidene]-1,3-thiazol-4-one
Molecular Formula: C18H24N2O2S
Molecular Weight: 332.46
 
Technical Data:
Appearance: Off-white to white crystalline powder
Solubility: Soluble in DMSO
Purity: >99%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Darbufelone:

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Biological Activity:
  1. Slow-binding inhibition of human prostaglandin endoperoxide synthase-2 with darbufelone, an isoform-selective antiinflammatory di-tert-butyl phenol.
 
References:
  1. Johnson, A.R., Marletta, M.A., Dyer, R.D. Biochemistry (2001)
 
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