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ICONC14160 LY450139(Semagacestat) (425386-60-3)
 
 
Catalog No.: C14160
CAS No.: 425386-60-3
Synonym: Semagacestat
Chemical Name:

(2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide
Molecular Formula:

C19H27N3O4
Molecular Weight: 361.44
 
Technical Data:
Appearance: White powder
Solubility: Soluble in DMSO and Methanol
Purity: >97%
Storage: at -20℃
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of LY450139(Semagacestat):

Size

Price

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10mg 

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50mg 

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100mg 

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Contact us for competitive discounts on bulk quantities
 
Biological Activity:

g-Secretase Inhibitor;Alzheimer's Disease
 
References:
Mitani Y, et al. Differential effects between γ-secretase inhibitors and modulators on cognitive function in amyloid precursor protein-transgenic and nontransgenic mice. J Neurosci. 2012 Feb 8;32(6):2037-50.
 
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