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ICONC13516 Cyclosporin B (63775-95-1)
 
 
Catalog No.: C13516
CAS No.: 63775-95-1
Synonym: Ala2-Cyclosporine
Chemical Name:

Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydrCyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-alanyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]oxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-alanyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]

Molecular Formula:

C61H109N11O12

Molecular Weight: 1188.60
 
Technical Data:
Appearance: Amorphous white Powder
Solubility: Soluble in ethanol
Purity: >95%
Storage: Store at room temperature
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Cyclosporin B:

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10mg 

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Contact us for competitive discounts on bulk quantities

 
Biological Activity:

An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

 
References:

1.Fang SH  et al. Pharmacokinetic and pharmacodynamic interactions of morin and cyclosporin. Toxicol Appl Pharmacol 205:65-70 (2005).

2.von Wartburg A & Traber R Cyclosporins, fungal metabolites with immunosuppressive activities. Prog Med Chem 25:1-33 (1988).

 
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