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ICONC13515 Cyclosporin A (59865-13-3)
 
 
Catalog No.: C13515
CAS No.: 59865-13-3
Synonym: Antibiotic S 7481F1; Cyclosporine
Chemical Name:

Cyclosporin A
Molecular Formula:

C62H111N11O12
Molecular Weight: 1202.62
 
Technical Data:
Appearance: White crystalline powder
Solubility: Soluble in DMSO and ethanol
Purity: >99%
Storage: at -20°C
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Cyclosporin A:

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Biological Activity:

Cyclic oligopeptide with immunosuppressant properties. Induces apoptosis in rat thymocytes and in the murine B cell lymphoma cell line, WEH1-231. However, prevents anti-IgM and ionomycin-induced apoptosis in BLB cell lines. The complex of cyclosporin A wi.
 
References:

1.Yu DY  et al. Effects of cyclosporin A, FK506 and rapamycin on calcineurin phosphatase activity in mouse brain. IUBMB Life 58:429-33 (2006).

2.Ho S  et al. The mechanism of action of cyclosporin A and FK506. Clin Immunol Immunopathol 80:S40-5 (1996).
 
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