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C13398 Bosutinib(SKI 606) (380843-75-4)

Catalog No.:	C13398
CAS No.:	380843-75-4
Synonym:	SKI-606
Chemical Name:	4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile
Molecular Formula:	C₂₆H₂₉Cl₂N₅O₃
Molecular Weight:	530.45

Technical Data:

Appearance:	White powder
Solubility:	Soluble in DMSO
Purity:	>99%
Storage:	at +4°C
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Bosutinib(SKI 606):

Size	Price	Stock
10mg	USD	In Stock
50mg	USD	In Stock
100mg	USD	In Stock

Biological Activity:

Inhibitors of SRC, ABL and TEC family kinases. It can cause a decrease in cell motility and invasion of breast.

References:

Rabbani SA et al. SKI-606 (Bosutinib) blocks prostate cancer invasion, growth, and metastasis in vitro and in vivo through regulation of genes involved in cancer growth and skeletal metastasis. Mol Cancer Ther 9:1147-57 (2010).

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