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ICONC13541 Daunorubicin Hydrochloride (23541-50-6)
 
 
Catalog No.: C13541
CAS No.: 23541-50-6
Synonym: daunomycin hydrochloride
Chemical Name:

(8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride

Molecular Formula:

C27H29NO10.HCl

Molecular Weight: 563.99
 
Technical Data:
Appearance: Orange red crystalline hygroscopic powder
Solubility: Slightly soluble in water or methanol, slightly soluble in ethanol (95%). Practically insoluble in chloroform or acetone
Purity: >99%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Daunorubicin Hydrochloride:

Size

Price

Stock

10mg 

USD

In stock 

50mg 

USD

In stock 

100mg 

USD

In stock 

Contact us for competitive discounts on bulk quantities

 
Biological Activity:

An anticancer agent used primarily for the treatment of leukemia. Forms covalent adducts with DNA. Triggers diacylglycerol and ceramide production in tumor cells and induces apoptosis.

 
References:
1.Bose R, Verheij M, Haimovitz-Friedman A, Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. Cell. 1995 Aug 11;82(3):405-14.
2. Fu Y, Zhou J, Li H, Daunorubicin induces procoagulant activity of cultured endothelial cells through phosphatidylserine exposure and microparticles release. Thromb Haemost. 2010 Dec;104(6):1235-41.
 
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