ICONHome   ICONContact us   ICONAdd Favorites
Biochemtek
Search Product
Live Chat E-mail
Pharmacology
ICON Inhibitors
ICON Receptors
ICON Hedgehog Signaling Pathway
ICON Stem Cells
ICON Signal Transduction
   More +
Research Area
ICON Cancer
ICON Antivirus
ICON Cardiovascular System
ICON Endocrinology
ICON Neuroscience
   More +
Product Type
ICON Natural Products
ICON Peptides
ICON Prostaglandins
ICON Vitamin D series compounds
ICON Toxins
   More +
Browse Alphabetically by Name
ALL A B C D E F
G H I J K L M
N O P Q R S T
U V W X Y Z Others
 
ICONC13530 Dapagliflozin(BMS-512148) (461432-26-8)
 
 
Catalog No.: C13530
CAS No.: 461432-26-8
Synonym: BMS-512148
Chemical Name:

(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol

Molecular Formula:

C21H25ClO6

Molecular Weight: 408.87
 
Technical Data:
Appearance:
Solubility: Soluble in DMSO
Purity: >98%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Dapagliflozin(BMS-512148):

Size

Price

Stock

10mg 

USD

In stock 

50mg 

USD

In stock 

100mg 

USD

In stock 

Contact us for competitive discounts on bulk quantities

 
Biological Activity:

Dapagliflozin is an experimental drug as a potential treatment for type 1 and 2 diabetes Although dapagliflozin's method of action would operate on either type of diabetes or other conditions resulting in hyperglycemia, the current clinical trials specifically exclude participants with Type 1 diabetes.

Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter causes blood glucose to be eliminated through the urine.

 
References:
 Bailey CJ, et al. Dapagliflozin monotherapy in drug-na?ve patients with diabetes: a randomized-controlled trial of low-dose range(?). Diabetes Obes Metab. 2012 Jul 6;9999(9999). doi: 10.1111/j.1463-1326.2012.01659.x.
 
View Related Products by Target:
Vandetanib(AZD6474)
Vorinostat(SAHA)
Tozasertib(VX-680)
Lenalidomide(CC-5013)
Teniposide(VM-26)
Pazopanib(GW-786034)
Trilostane
CYC-116
Gemcitabine HCL
Bicalutamide
Sorafenib Tosylate
Sunitinib Malate(Sutent)
 
 

Keywords: Buy Dapagliflozin(BMS-512148) | Dapagliflozin(BMS-512148) Supplier | Purchase Dapagliflozin(BMS-512148) | Dapagliflozin(BMS-512148) Cost | Dapagliflozin(BMS-512148)  Manufacturer | Order Dapagliflozin(BMS-512148) | Dapagliflozin(BMS-512148) Distributor | Dapagliflozin(BMS-512148) Structure, Chembest

Buy 461432-26-8| 461432-26-8 Supplier | Purchase 461432-26-8 | 461432-26-8 Cost | 461432-26-8 Manufacturer | Order 461432-26-8 | 461432-26-8 Distributor | 461432-26-8 Structure, Chembest  

Products are for research use only. Not for human use. We do not sell to patients.
Copyright © 2010-2013 Chembest Research Laboratories. All Rights Reserved
E-mail:sales@biochembest.com