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ICONC13584 BIBR-796(Doramapimod) (285983-48-4)
 
 
Catalog No.: C13584
CAS No.: 285983-48-4
Synonym: BIRB-796 BS, BIRB-0796, BIRB-796
Chemical Name:

1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea

Molecular Formula:

C31H37N5O3

Molecular Weight: 527.67
 
Technical Data:
Appearance:
Solubility: Soluble in DMSO and Ethanol
Purity: >99%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of BIBR-796(Doramapimod):

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10mg 

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50mg 

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100mg 

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Contact us for competitive discounts on bulk quantities

 
Biological Activity:

Small molecule inhibitor of p38 mitrogen-activated protein (MAP) kinase (MAPK); more potent than SB 203580 on p38α and p38β MAPKs; potential agent for the treatment of inflammatory diseases.

 

 
References:

  Pargellis C, et al. Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site. Nat Struct Biol, 2002, 9(4), 268-272.

 

 
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