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ICONC14308 Vadimezan(DMXAA) (117570-53-3)
 
 
Catalog No.: C14308
CAS No.: 117570-53-3
Synonym: NSC-640488,ASA404,DMXAA
Chemical Name:

5,6-Dimethylxantheonone-4-acetic acid; 2-(5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid

Molecular Formula:

C17H14O4

Molecular Weight: 282.29
 
Technical Data:
Appearance: White powder
Solubility: Soluble in DMSO
Purity: >98%
Storage: at +4°C
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Vadimezan(DMXAA):

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10mg 

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50mg 

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100mg 

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Contact us for competitive discounts on bulk quantities

 
Biological Activity:

Vadimezan or ASA404 (originally DMXAA) is a tumor-vascular disrupting agent(tumor-VDA) that attacks the blood supply of a cancerous tumor to cause tumor regression.It is being studied for the treatment of prostate cancer and HER2 -negative metastatic breast cancer.

 
References:
Tang CK  et al. The chemotherapeutic agent DMXAA as a unique IRF3-dependent type-2 vaccine adjuvant.PLoS One 8:e60038 (2013). 
 
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