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C13295 Anastrozole(Arimidex) (120511-73-1)

Catalog No.:	C13295
CAS No.:	120511-73-1
Synonym:	ZD1033; ZD 1033; ZD-1033
Chemical Name:	Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile
Molecular Formula:	C₁₇H₁₉N₅
Molecular Weight:	293.37

Technical Data:

Appearance:
Solubility:	Soluble in DMSO and Ethanol
Purity:	>99%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Anastrozole(Arimidex):

Size	Price	Stock
10mg	USD	In stock
50mg	USD	In stock
100mg	USD	In stock

Biological Activity:

Anastrozole, which contains a triazole functional group, reversibly binds to the cytochrome P-450 component of aromatase.

Binding interferes with the catalytic properties of aromatase,which results in inhibition of estrogen synthesis.

References:

1. Dukes M, et al. The preclinical pharmacology of "Arimidex" (anastrozole; ZD1033)--a potent, selective aromatase inhibitor. J Steroid Biochem Mol Biol. 1996 Jul;58(4):439-45.
2. Plourde PV, et al. Arimidex: a potent and selective fourth-generation aromatase inhibitor. Breast Cancer Res Treat. 1994;30(1):103-11.

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