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ICONC14273 Tobramycin(Tobramycin Base) (32986-56-4)
 
 
Catalog No.: C14273
CAS No.: 32986-56-4
Synonym: 1-epitobramycin
Chemical Name:
3’-deoxykanamycinb;4-[2,6-diamino-2,3,6-trideoxy-alpha-d-glycopyranosyl]-6-[3-amino-3-deoxy-alpha;6-trideoxy-alpha-d-ribo-hexopyranosyl-(1-4))-2-deoxy-;d-6-trideoxy-alpha-d-ribohexopyranosyl-(1-6))-2-deoxy;d-6-tyrideoxy-alpha-d-ribohexopyranosyl-(1-6))-2-deoxy;deoxykanamycinb;-d-glycopyranosyl]-2-deoxystreptamine
Molecular Formula: C18H37N5O9
Molecular Weight: 467.51
 
Technical Data:
Appearance:
Solubility: Soluble in DMSO and Ethanol
Purity: >98%
Storage: at -20℃ 2 years
Original QC Data:
Shipping Conditions: Ambient Temp.
 
Price and Availability of Tobramycin(Tobramycin Base):

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Biological Activity:

Inhibits ribosomal translation. Aminoglycoside antibiotic which binds 30S ribosomal subunit A, preventing functional protein production. Effective against gram-negative bacteria.

 
References:
Pignatello R  et al. Amphiphilic ion pairs of tobramycin with lipoamino acids. Eur J Med Chem 46:1665-71 (2011).
 
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