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Pharmacology

Inhibitors

Receptors

Hedgehog Signaling Pathway

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Cardiovascular System

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Vitamin D series compounds

Toxins

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C13818 Licofelone(ML-3000) (156897-06-2)

Catalog No.:

C13818

CAS No.:

156897-06-2

Synonym:

ML-3000

Chemical Name:

2-[2-(4-Chlorophenyl)-6,6-dimethyl-1-phenyl-5,7-dihydropyrrolizin-3-yl]acetic acid; [2,2-Dimethyl-6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl]acetic acid

Molecular Formula:

C₂₃H₂₂ClNO₂

Molecular Weight:

379.88

Technical Data:

Appearance:
Solubility:	Soluble in DMSO
Purity:	>98%
Storage:	at -20℃ 2 years
Original QC Data:
Shipping Conditions:	Ambient Temp.

Price and Availability of Licofelone(ML-3000):

Size	Price	Stock
10mg	USD	In stock
50mg	USD	In stock
100mg	USD	In stock

Biological Activity:

Licofelone is an anti-inflammatory and dual inhibitor of cyclooxygenase and 5-LO(5-lipoxygenase). Licofelone inhibits both Cox-1 and Cox-2.

References:

Laufer, S.A., et al.: J. Med. Chem., 37, 1894 (1994) Tries, S., et al.: Inflamm. Res., 51, 135 (2002) Moreau, M., et al.: J. Vet. Pharmacol. Ther., 28, 81 (2005).

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